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News / MSC Cruises to offer brand-new year-round itinerary from new La Romana, Dominican Republic, homeport
MSC Opera will operate a brand-new itinerary, operating weekly departures, and guests can opt to book a seven-night sailing or extend their cruise to a back-to-back 14-night ‘butterfly’ cruise

At Fitur, the International Tourism Trade Fair taking place in Madrid, Spain, MSC Cruises spoke of their new year-round operation from La Romana, Dominican Republic, starting in November 2026.
In the presence of the Dominican Republic Minister of Tourism, David Collado, the cruise line committed its year-round operation from a brand-new homeport in La Romana, in the south of the Dominican Republic for the long term. This is the first time MSC Cruises has offered year-round sailings in the Southern Caribbean.
MSC Opera will operate a brand-new itinerary, operating weekly departures, and guests can opt to book a seven-night sailing or extend their cruise to a back-to-back 14-night ‘butterfly’ cruise.
Sailings are already available to book, with the first cruise departing on November 16, 2026. For full itinerary information, visit MSC Cruises’ website.
One of the highlights of this new itinerary is the call to Catalina Island, close to the shores of the Dominican Republic, offering guests an exclusive nature reserve experience. Pristine white sand beaches and crystal-clear waters allow guests to relax and unwind, or the more adventurous can snorkel the surrounding coral reefs to view their diverse ecosystems.
With multiple international airports, The Dominican Republic offers convenient connections from all over the world. MSC Opera’s program will bring 120,000 international visitors to La Romana each year, meaning 240,000 in-bound and out-bound flight passengers, and a boost to hotels, restaurants, bars and businesses in the surrounding areas.
Some of MSC Opera’s new itinerary highlights include:
- La Romana, Dominican Republic: La Romana offers visitors a perfect blend of relaxation, rich culture and natural beauty featuring pristine beaches, local craft shops, delicious seafood and easy access to renowned sites such as the enchanting Cueva de las Maravillas 16th-century Mediterranean inspired village Altos de Chavón.
- Catalina Island, Dominican Republic: Catalina Island is the ideal tropical paradise for a memorable vacation for both relaxation and adventure. The island is known for its crystal-clear waters, vibrant coral reefs and white sandy beaches perfect for snorkeling or sunbathing. Alternatively, book a scenic boat trip excursion to Saona Island, located in the Cotubanamá National Park and known for its mangroves and coral reefs.
- Fort-de-France, Martinique: Martinique delights visitors from around the world with its renowned natural wonders, historical charm and beautiful bays and beaches. In the vibrant capital of Fort-de-France, guests can explore colorful architecture, lively markets and local shops, or venture further off to discover the island’s famous rum distilleries, lush rainforest and unique beaches.
- Virgin Gorda, British Virgin Islands: Virgin Gorda is one of the British Virgin Islands’ most picturesque and serene destinations, offering an unforgettable Caribbean escape. Visitors can explore its world-famous Baths, relax on pristine beaches, or enjoy scenic hiking trails such as Gorda Peak National Park for stunning island views.
- John’s, Antigua and Barbuda: Saint John’s is the capital city of Antigua and Barbuda renowned for vibrant, colorful houses, captivating historical landmarks such as Fort James fortress, and the gateway to some of the Caribbean’s most gorgeous beaches – perfect for relaxing in the sun or enjoying water activities.











